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DaithaiC says : Kos is one of the most popular islands of the Dodecanese. Geographically speaking it is very close the Asia Minor and therefore a significant commercial and cultural center. At a comparatively early period Jews are mentioned among the population of Kos; and under Alexander the Great and the Egyptian Ptolemies (from 336 B.C.) the town developed into one of the great Jewish centres in the Ægean.