Cytogenetics

[Original articles] Integration of conventional cytogenetics, comparative genomic hybridisation and interphase fluorescence in situ hybridisation for the detection of genomic rearrangements in acute leukaemia

Aims: To screen for genomic imbalances in patients with acute leukaemia using conventional (G-banding) and molecular (comparative genomic hybridisation (CGH) and fluorescence in situ hybridisation (FISH)) methods to determine whether an integrative screening approach increases abnormality detection rate. Methods: G-banded analysis was performed on unstimulated bone marrow (BM) or peripheral blood (PB) cells after short-term (24-hour) culture. CGH was performed on reference (control) and neoplas...

Head of the Cancer Cytogenetics Laboratory

myScience.ch - Lausanne - The Faculty of Biology and Medicine of the University of Lausanne (UNIL), Switzerland and the University Medical Centre of Lausanne (CHUV) invite applications for the position of Head of the Cancer Cytogenetics...

Isoderivative chromosome 20 in bone marrow: three new cases.

Related Articles Isoderivative chromosome 20 in bone marrow: three new cases. Cancer Genet Cytogenet. 2008 Jul;184(1):72-3 Authors: Shetty S, Roland B PMID: 18558294 [PubMed - in process] (Source: Cancer Genetics and Cytogenetics)

Technical Director - Cytogenetics

Recommends changes for laboratory to improve performance and/or correct any deficiencies as needed. Gives overall direction and serves as technical advisor to assigned clinical laboratories. Job Requirements : Ph.D. or MD Board Certified in Anatomic & Clinical Path preferred w/6 years of experience in related field. Must meet CLIA requirements.For more information, please click here To visit us at BiotechCrossing. For further information, please visit us online at http://www.biotechcrossing….

Simultaneous occurrence of t(9;22)(q34;q11.2) and t(16;16)(p13;q22) in a patient with chronic myeloid leukemia in blasti...

Related Articles Simultaneous occurrence of t(9;22)(q34;q11.2) and t(16;16)(p13;q22) in a patient with chronic myeloid leukemia in blastic phase. Cancer Genet Cytogenet. 2008 Jun;183(2):109-13 Authors: Zámecníkova A, Al Bahar S, Ramesh P Coexistence of two specific chromosomal translocations in the same clone is an infrequent phenomenon and has only rarely been reported in hematological malignancies. We report a combination of t(16;16)(p13;q22), the Philadelphia translocation t(9;22)(q34;q11.2...

The italian external quality assessment scheme in classical cytogenetics: four years of activity

Community Genet 2008;11:295-303 (DOI:10.1159/000121401) (Source: Community Genetics)

Cytogenetics Technologist (New York Presbyterian Hospital)

Location: New York,NY Source: Jobs.net

Perspectives on the formation of radiation-induced exchange aberrations.

DNA repair, Vol. 5, No. 9-10. (8 September 2006), pp. 1182-1191. Controversy surrounding the proposed mechanism of radiation-induced translocation has existed virtually since the inception of radiation genetics/cytogenetics, some 75 years ago. Chief among these controversies is how close chromosomes have to be to one another at the time of exposure for an exchange to occur. An historically related issue, and one that continues to generate lively debate, is whether both chromosomes participating ...

[original articles] comparison of targeted and whole genome analysis of postnatal specimens using a commercially availab...

Purpose: The University of Utah Comparative Genomic Hybridization Microarray Laboratory was one of the first US laboratories to offer comparative genomic hybridisation (CGH) microarray testing using a commercial platform in a clinical setting. Results for 1076 patients (1598 chips) are presented. Methods: The Spectral Genomics/PerkinElmer Constitutional ChipTM (targeted array), SpectralChip 2600TM (whole genome array) and a "Combo" chip (both arrays run simultaneously) were the tests offered. Ab...

Molecular biology of the gene / James D. Watson ... [et al.].

Language: English Edition: 6th ed. Published/Distributed: San Francisco : Pearson/Benjamin Cummings ; Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, c2008. Subject(s): Cytogenetics. Gene Expression Regulation. Gene Expression. Genetic Techniques. Molecular Biology. Molecular biology. Molecular genetics. Location: Biomed Library: QH506 .M761 2008